1) An archaic word for grandfather, or less precisely forefather.
1455 John of Barton my granncesire [sic], Whenby
1466 with all my fadir, graunsir and auncestres in small skochons at my hede, Leeds
1543 all his meases ... which had belonged to Thomas Gledhyll his father and John Gledhyll his grandsir, Barkisland
1575 I dyd pay to Edward Clearson of Ivelet for is grannser [sic] winding sheatt 2s 8d, Grinton.